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Simple test could cut excessive antibiotic use

February 25, 2010

Times Live
By Reuters


If doctors used an existing simple lab test on patients with coughs or flu-like symptoms they would be better able to decide which of them might benefit from antibiotics, scientists say.

They said prescriptions of expensive antibiotics for respiratory tract infections could be reduced by more than 40% if tests became more commonplace.

The German researchers found that testing for a marker of bacterial infection known as procalcitonin (PCT) helped identify patients whose respiratory tract infections would respond to antibiotics, and stopped others being offered unnecessary drugs.

Respiratory infections are very common and doctors are taught to prescribe antibiotics on the basis of features like sputum or fever, which suggest there may be bacterial infection.

But this judgment is not always easy, the researchers said, and lab tests can help sort bacterial from viral infections.

Excessive prescribing of antibiotics adds to healthcare costs and to the worldwide problem of multi-drug resistant bacteria, or "superbugs", like MRSA. Superbugs kill about 25 000 people a year in Europe and 19 000 in the United States.

Experts say varying patterns of antibiotic resistance around Europe are strongly linked to varied prescription habits among doctors, and more concrete guides are desperately needed.

The European Centre for Disease Prevention and Control said last year that overuse of antibiotics in the region was building widespread resistance to a level with could threaten modern medicine.

In a study in the European Respiratory Journal, Tobias Welte of Hannover Medical School said "a simple PCT-guided strategy of decisions on antibiotic treatment" could cut the antibiotic treatment rate by more than 40% with no risk to patients.

This is a portion of the original article. To keep reading, visit timeslive.co.za


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